Immune drug doesn't help kids with hard-to-treat kidney disorder
The drug rituximab, an antibody that targets the immune system and is often used to treat immune disorders such as lymphoma and arthritis, has recently emerged as a potential treatment for a childhood...
View ArticleResearchers reveal most effective treatment for common kidney disorder
The results of a pioneering UK-wide clinical trial that compared treatments for patients with a common type of kidney disease has found one to be significantly more effective. The results of the study,...
View ArticleKidney disease mutations found in a genomic blind spot
(Medical Xpress)—Advances in DNA sequencing technology during the past decade have given scientists powerful tools to peer into the genomes of humans and other species. Despite the efficiency and...
View ArticleResearchers link facial structure to kidney disease
(Medical Xpress)—Researchers at King's College London's Dental Institute have shown that people with a certain kind of kidney disease have characteristic facial features that may reflect the genetic...
View ArticlePatients with a certain form of kidney disease may have a reduced risk of cancer
Patients with a certain form of kidney disease may have a reduced risk of cancer compared with patients with other kidney diseases, according to a study appearing in an upcoming issue of the Journal of...
View ArticleIs obesity a ciliopathy, triggered by malfunctioning primary cilia?
Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and...
View ArticleScientists study human diseases in flies
More than two-thirds of human genes have counterparts in the well-studied fruit fly, Drosophila melanogaster, so although it may seem that humans don't have much in common with flies, the...
View ArticleExperts see hopeful signs on eating disorders
April Dunlap was 17 and weighed 165 pounds when she began a diet and exercise regimen. After three months, the 5-foot-5 teen had lost the 20 pounds she had hoped to shed. But she kept going. "It was...
View ArticleBlocking LRRK2 activity is not a simple answer to Parkinson's disease
Mutations in the LRRK2 gene are the most common cause of genetic Parkinson's disease (PD). New research published in BioMed Central's open access journal Molecular Neurodegeneration demonstrates that...
View ArticleImmune drug helps patients with serious kidney disorder
A drug commonly used to treat immune disorders such as lymphoma and arthritis also benefits patients with an immune disorder of the kidneys that can lead to kidney failure, according to a study...
View ArticleBiochemists open path to molecular 'chaperone' therapy for metabolic disease
University of Massachusetts Amherst researchers, experts in revealing molecular structure by X-ray crystallography, have identified two new small "chaperone" molecules that may be useful in treating...
View Article'World-first' surgery gives Australian boy new hope
Australian doctors Thursday hailed what they described as a world-first surgical treatment for a boy suffering from a rare disease that sends his blood pressure soaring and triggered a stroke.
View ArticleSurprising genetic link between kidney defects and neurodevelopmental...
About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study by Columbia University Medical...
View ArticleA new treatment for kidney disease-associated heart failure?
Chronic kidney disease (CKD) patients frequently suffer from mineral bone disorder, which causes vascular calcification and, eventually, chronic heart failure. Similar to patients with CKD, mice with...
View ArticleKidneys sometimes removed unnecessarily due to misdiagnosis of genetic disorder
Thousands of individuals have had kidneys removed unnecessarily because doctors misdiagnosed their disease.
View ArticleFacts on 'bute', pain drug found in horsemeat
Phenylbutazone, a painkiller for horses, can cause blood disorders in humans but at doses much higher than any one person is likely to ingest from eating horsemeat.
View ArticleEU releases 144 mn euro for new rare disease research
The European Union on Thursday pledged 144 million euros of fresh funding for research on rare diseases that currently affect some 30 million Europeans, the majority of them children.
View ArticleNew approaches in treating complicated childhood polycystic kidney disease
A collaborative team of physician-scientists at the Medical College of Wisconsin (MCW) and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to...
View ArticleSurprising mechanism discovered in polycystic kidney disease
A study by Yale researchers has uncovered a new and unexpected molecular mechanism in the development of polycystic kidney disease, or PKD. The study appears in Nature Genetics.
View ArticleRare eye disease leaves people without an iris
(HealthDay)—You may never have heard of aniridia, a genetic disorder that robs people of their vision. But researchers studying the condition say it could give insight into some common health...
View ArticleAmgen may buy cancer drug maker Onyx for $10.5B
Biotech drugmaker Amgen is reportedly close to buying cancer drug maker Onyx Pharmaceuticals for about $10.5 billion.
View ArticleNew study paints grim health picture for obese teens
(HealthDay)—Severely obese teens are at increased risk for a host of serious health problems as adults, including asthma, kidney disease and sleep disorders, according to a new study.
View ArticleUnderstanding a molecular motor responsible for human development
Another mystery of the human body has been solved by scientists who have identified how a molecular motor essential for human development works. They have also pinpointed why mutations in genes linked...
View ArticleNew technique provides novel approach to diagnosing ciliopathies
Cilia, the cell's tails and antennas, are among the most important biological structures. They line our windpipe and sweep away all the junk we inhale; they help us see, smell and reproduce. When a...
View ArticleAnxiety is an underrecognized yet serious clinical problem for dialysis patients
A new review looks at the potential effects of anxiety on a vulnerable patient population: individuals undergoing hemodialysis for the treatment of kidney failure. The review, which appears in an...
View Article'Teashirt' gene links autism and kidney problems, new study finds
A gene dubbed the 'Teashirt' by its discoverers has been identified as a link between children with kidney problems and autism, in a new study which has implications for how doctors working on both...
View ArticleShort and poor quality sleep may have negative effects on kidney function
Not getting enough quality sleep was linked with worsening kidney function in a study of patients with chronic kidney disease. The findings will be presented at ASN Kidney Week 2016 November 15-20 at...
View ArticleDo best-selling drugs that calm stomachs damage kidneys? The answer's unclear
Sherry Herman was watching TV when the ad popped up on the screen. Lawyers were seeking clients for a class-action lawsuit, suggesting a link between certain heartburn pills and chronic kidney disease...
View ArticlePoor sleep hastens progression of kidney disease
People with chronic kidney disease may be especially vulnerable to the deleterious effects of poor sleep, according to a new paper published in the Journal of the American Society of Nephrology.
View ArticleSertraline treatment no benefit for depressive symptoms in CKD
(HealthDay)—Sertraline treatment does not significantly improve depressive symptoms among patients with non-dialysis-dependent chronic kidney disease (CKD) and major depressive disorder (MDD),...
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